Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

¹Ì°¢ Àå¾Ö ȯÀÚÀÇ ÀÓ»óÀû Ư¼º¿¡ °üÇÑ ¿¬±¸

Clinical Characteristics of Patients with Taste Disorders

´ëÇѱ¸°­³»°úÇÐȸÁö 2009³â 34±Ç 4È£ p.341 ~ 351
ÀÌÀºÁø, ¹Ú¿ø±Ô, ³²Áø¿ì, À±Á¾ÀÏ, °íÈ«¼·,
¼Ò¼Ó »ó¼¼Á¤º¸
ÀÌÀºÁø ( Lee Eun-Jin ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÁø´ÜÇб³½Ç
¹Ú¿ø±Ô ( Park Won-Kyu ) - ¼­¿ï´ëÇб³ Ä¡°ú´ëÇÐ ±¸°­³»°úÁø´ÜÇб³½Ç
³²Áø¿ì ( Nam Jin-Woo ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°­³»°úÁø´ÜÇб³½Ç
À±Á¾ÀÏ ( Yun Jong-Il ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°­³»°úÁø´ÜÇб³½Ç
°íÈ«¼· ( Kho Hong-Seop ) - ¼­¿ï´ëÇб³ Ä¡ÀÇÇдëÇпø ±¸°­³»°úÁø´ÜÇб³½Ç

Abstract

»ç¶÷µéÀº ¹Ì°¢À» ÅëÇØ À½½Ä¹°ÀÇ ¿µ¾çºÐ°ú ¾ÈÀü¼º ¿©ºÎ¸¦ ÆľÇÇÏ°í, À̸¦ ÅëÇØ ½Ä¿åÀÌ ÀÚ±ØµÇ°í ¸¸Á·µÇ¹Ç·Î ¹Ì°¢Àº À½½Ä¹°À» ¼·ÃëÇϴµ¥ ÇʼöÀûÀÎ ¿ªÇÒÀ» ÇÑ´Ù°í ÇÒ ¼ö ÀÖ´Ù. ¹Ì°¢ÀÌ »ó½ÇµÇ°Å³ª ¿Ö°îµÈ ȯÀÚµéÀÇ °æ¿ì ¼·½Ä ¾ç»ó¿¡ º¯È­¸¦ ÀÏÀ¸ÄÑ °Ç°­¿¡ ³ª»Û ¿µÇâÀ» ¹ÌÄ¡°Ô µÉ ¼ö ÀÖ´Ù. ¹Ì°¢ ±â´É¿¡ ¿µÇâÀ» ÁÙ ¼ö ÀÖ´Â ¿ä¼Ò´Â ¸Å¿ì ´Ù¾çÇÏ¸ç ¹Ì°¢ÀÇ Àå¾Ö ¾ç»ó ¶ÇÇÑ ¸Å¿ì ´Ù¾çÇÏ°Ô ³ªÅ¸³¯ ¼ö ÀÖ´Ù. ÇÏÁö¸¸ ¹Ì°¢Àº ÁÖ°üÀûÀÎ °¨°¢À¸·Î ´Ù¸¥ °¨°¢µé°ú´Â ´Þ¸® °´°üÀûÀ¸·Î Æò°¡ÇϱⰡ ±î´Ù·Î¿ì¸ç, ¸ÀÀ» ´À³¢´Âµ¥ À־ ¹Ì°¢»Ó ¾Æ´Ï¶ó ÈÄ°¢, ÃË°¢, ¿Âµµ°¨°¢, ½É¸® »óÅ µî ¿©·¯ ´Ù¸¥ ¿ä¼ÒµéÀÇ ¿µÇâÀ» ¹ÞÀ¸¹Ç·Î ¹Ì°¢ ÀÌ»óÀ» ³ªÅ¸³»´Â ȯÀÚµéÀ» Áø´ÜÇÏ°í Ä¡·áÇÏ´Â °ÍÀº ¸Å¿ì ¾î·Á¿î ÀÏÀÌ´Ù. ±×·¯¹Ç·Î ½ÇÁ¦ ÀÓ»óÀû »óȲ¿¡¼­ ¹Ì°¢Àå¾ÖÀÇ Æò°¡¸¦ À§Çؼ­´Â ¹«¾ùº¸´Ùµµ ½ÅÁßÇÏ°í öÀúÇÑ º´·ÂûÃë¿Í ÀÓ»óÀû Áõ»óÀÇ ºÐ¼®À» ÅëÇÏ¿© ȯÀÚÀÇ »óŸ¦ Á¤È®È÷ Æò°¡ÇÏ´Â °ÍÀÌ °¡Àå Áß¿äÇÏ´Ù. ¹Ì°¢Àº ½Ã°¢À̳ª û°¢°ú °°Àº ´Ù¸¥ °¨°¢¿¡ ºñÇØ ±× µ¿¾È ÁÖ¸ñÀ» ¹Þ¾Æ¿ÀÁö ¸øÇÑ ºÐ¾ß¿´À¸³ª, »çȸ°¡ ¹ß´ÞÇÔ¿¡ µû¶ó »îÀÇ ÁúÀ» Áß½ÃÇÏ°Ô µÊÀ¸·Î½á ÃÖ±Ù ¹Ì°¢ Àå¾Ö·Î ³»¿øÇϴ ȯÀÚ°¡ Áõ°¡ÇÏ´Â Ãß¼¼ÀÌ´Ù. º» ¿¬±¸ÀÇ ¸ñÀûÀº ¹Ì°¢ Àå¾Ö¸¦ ÁÖ¼Ò·Î ³»¿øÇÑ È¯ÀÚµéÀÇ ÀÓ»óÀû Ư¼ºÀ» ºÐ¼®ÇÏ´Â °ÍÀÌ´Ù.
¹Ì°¢ Àå¾Ö¸¦ ÁÖ¼Ò·Î 2005³â 11¿ùºÎÅÍ 2008³â 8¿ù±îÁö ¼­¿ï´ëÇб³ Ä¡°úº´¿ø ±¸°­³»°ú¿¡ ³»¿øÇÑ È¯ÀÚ 50¸í(³² 12¸í, ¿© 38¸í, Æò±Õ ¿¬·É 53.6 ¡¾ 14.7 ¼¼)À» ´ë»óÀ¸·Î ÇÏ¿´´Ù. »ó´ãÀ» ÅëÇÏ¿© ÇöÀç ¹Ì°¢ Àå¾ÖÀÇ Áõ»ó°ú °ü·ÃµÈ »çÇ×µé°ú ±× ¹ÛÀÇ ÀÇ°úÀû¤ýÄ¡°úÀû º´·Â, Åõ¾à, ¹Ì°¢ Àå¾Ö ¿ÜÀÇ ±¸°­ Áõ»óµé¿¡ ´ëÇÏ¿© Á¶»çÇÏ¿´À¸¸ç, ±¸°­ °ËÁø, ¼³¹®Áö ÀÛ¼º, ¹æ»ç¼± »çÁø ÃÔ¿µ, Ç÷¾×°Ë»ç, Ÿ¾×ºÐºñÀ² ÃøÁ¤ °Ë»ç µîÀÇ ÀÓ»óÀû °Ë»ç¸¦ ½ÃÇàÇÏ¿© ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù.
1. ¹Ì°¢ Àå¾Ö ȯÀÚµé Áß ±¸°­ Á¡¸·ÀÇ ÅëÁõ ȤÀº ÀÛ¿­°¨À» È£¼ÒÇÑ È¯ÀÚ°¡ 36¸í(72%)À̾ú´Ù. À̵é Áß ±¸°­Á¡¸·¿¡ Ưº°ÇÑ º´¼Ò¸¦ º¸ÀÌÁö ¾Ê´Â ±¸°­ÀÛ¿­°¨ÁõÈıºÀ¸·Î Áø´ÜµÈ ȯÀÚ´Â 18¸í(36%)À̾ú´Ù.
2. Àüü ȯÀÚµé Áß 19¸í(38%)ÀÇ È¯ÀÚ°¡ ÁÖ°üÀû ±¸°­°ÇÁ¶°¨À» È£¼ÒÇÏ¿´À¸¸ç, Ÿ¾×ºÐºñÀ² ÃøÁ¤ °á°ú ºñÀڱؽà Ÿ¾×ºÐºñÀ²ÀÌ 0.1 mL/min ÀÌÇÏÀΠȯÀÚ´Â 14¸í(28%)À̾ú°í, Àڱؽà Ÿ¾×ºÐºñÀ²ÀÌ 0.5 mL/min ÀÌÇÏÀΠȯÀÚ´Â 17¸í(34%)À̾ú´Ù.
3. ¹Ì°¢ Àå¾ÖÀÇ Á¾·ù·Î´Â ¹Ì°¢°¨¼Ò(hypogeusia)°¡ 25¸í(50%)À¸·Î °¡Àå ¸¹¾ÒÀ¸¸ç, ¹Ì°¢¿Ö°î(dysgeusia)ÀÌ 18¸í(36%), ȯ»ó¹Ì°¢ (phantogeusia)ÀÌ 15¸í(30%), ¹Ì°¢°ú¹Î(hypergeusia)ÀÌ 10¸í(20%), ¹Ì°¢»ó½Ç(ageusia)ÀÌ 5¸í(10%) À̾ú´Ù. Àüü 50¸í Áß 19¸í(38%)ÀÇ È¯ÀÚ°¡ µÎ °¡Áö ÀÌ»óÀÇ ¹Ì°¢ Àå¾ÖÀÇ Á¾·ù¸¦ ³ªÅ¸³»¾úÀ¸¸ç, °¡Àå ¸¹Àº Á¶ÇÕÀº ¹Ì°¢¿Ö°î°ú ¹Ì°¢°¨¼Ò¸¦ °°ÀÌ º¸ÀÌ´Â °æ¿ì¿´´Ù.
4. ¹Ì°¢ Àå¾ÖÀÇ ¿øÀÎÀ̳ª °ü·Ã¿äÀÎÀº º´·ÂÁ¶»ç¿Í ÀÓ»ó°Ë»ç¸¦ Åä´ë·Î Æò°¡ÇÏ¿´À¸¸ç, ±¸°­Á¡¸·ÁúȯÀ̳ª ¿øÀκҸíÀÎ °æ¿ì°¡ °¢°¢ 9¸í(18%)À¸·Î °¡Àå ¸¹¾Ò´Ù. ±× ¹Û¿¡ ½ÉÀμºÀÌ 8¸í(16%), ¾à¹°ÀÌ 7¸í(14%), ±¸°­°ÇÁ¶ÁõÀÌ 6¸í(12%)À¸·Î ³ªÅ¸³µÀ¸¸ç, ÀÌ 5°¡ÁöÀÇ Ç׸ñÀÌ ÀüüÀÇ 78%¸¦ Â÷ÁöÇÏ¿´´Ù.

There is tremendous variability in the ways patients present with taste problems. Because of complex and multifactorial etiological background, it is not simple to evaluate patients with taste disorders. Accurate assessment of patients¡¯ status by prudent, thorough history taking and symptom analysis is the most essential for exact diagnosis of taste disorders. The aim of this study was to investigate the clinical characteristics of patients with taste problems as a primary complaint. Consecutive series of 50 patients (12 males and 38 females, mean age 53.6 ¡¾ 14.7 years) were included for the present study. All subjects were requested to complete a comprehensive questionnaire. Clinical evaluation procedures included oral examination, interview, questionnaire analysis, panoramic radiography, blood test and measurement of salivary flow rate.
The obtained results were as follows:
1. Among the patients, 36 patients (72%) complained of oral mucosal pain or burning sensation. Of these patients, 18 patients (36%) were diagnosed as burning mouth syndrome.
2. Nineteen patients (38%) complained of subjective oral dryness. The flow rate of unstimulated whole saliva was less than 0.1 mL/min in 14 patients (28%) and 17 (34%) had a stimulated whole salivary flow rate of less than 0.5 mL/min.
3. Among the types of taste disorders, hypogeusia, the most frequently reported, was found in 25 patients (50%), dysgeusia in 18 patients (36%), phantogeusia in 15 patients (30%), hypergeusia in 10 patients (20%), and ageusia in 5 patients (10%). Nineteen patients (38%) reported more than one type of taste disorder and the most frequent combination was dysgeusia + hypogeusia (n=6, 12%).
4. Based on data from the medical and dental histories and examinations, the patients were assigned to 12 probable causal categories. Taste disorders due to oral mucosal diseases and idiopathic taste disorder were the most frequent (n=9; 18%, each), followed by psychogenic taste disorder (n=8; 16%), drug-induced taste disorder (n=7; 14%), and taste disorder due to dry mouth (n=6; 12%). These 5 categories of taste disorder accounted for 78% of all cases in this study.

Å°¿öµå

¹Ì°¢ Àå¾Ö;ÀÓ»óÀû Ư¼º;±¸°­ÀÛ¿­°¨ÁõÈıº
Taste disorder;Clinical characteristics;Burning mouth syndrome

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

  

µîÀçÀú³Î Á¤º¸

KCI